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These episodes are distinct from nightmares, mainly occurring in the first half of the night, while nightmares often occur during REM sleep in the early morning hours

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Gene expression scope: Pickart and Margolina, using the Broad Institute's Connectivity Map database, reported that GHK-Cu appears to modulate expression of over 4,000 human genes, skewing toward anti-inflammatory, collagen-synthetic, DNA-repair, and anti-apoptotic gene sets