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With genomes of arthropod species available, gene number variation in each class of cytosolic GSTs has been observed in different species (Table 1)

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Because all patients were treated with IL-17 or TNF inhibitors, we focused on DMPs in genes related to the IL-17/TNF pathway using the WikiPathways database ( Figure 5C ) and an inverse correlation between methylation scores and PASI scores was observed (R=−0.72, p=0.008, Figure 5D )