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Preclinical Research Dosing Models Animal model studies have explored GHK-Cu at the following ranges: Topical (in vitro/ex vivo): 10–100 µM concentrations in cell culture media Subcutaneous (rodent models): 1–5 mg/kg body weight, administered 1–2x daily Wound healing models: Local application at 1–10 µg/wound site Reconstitution for Research GHK-Cu is typically supplied as a lyophilized powder